Monthly Publication Highlights

2022 Highlights

Drs. Bo Cai and Casey Krusemark

Multiplexed Small Molecule Ligand Binding Assays by Affinity Labeling and DNA Sequence Analysis”, which can be read in Angew Chem Int Ed Engl (January, 2022; doi: 10.1002/anie.202113515)

2019 Highlights

Drs. Elizabeth Topp and Tony Zhou

Effects of drying method and excipient on structure and stability of protein solids using solid-state hydrogen/deuterium exchange mass spectrometry (ssHDX-MS)

Dr. Yoon Yeo

Camouflaging Nanoparticles for Ratiometric Delivery of Therapeutic Combinations”

Dr. Kimberly Plake

Impact of a teaching objective structured clinical examination (TOSCE) on student confidence in a pharmacy skills laboratory”

Dr. Daniel Flaherty

Optimization of a 1,3,4-oxadiazole series for inhibition of Ca2+/calmodulin-stimulated activity of adenylyl cyclases 1 and 8 for the treatment of chronic pain

Dr. Emily Dykhuizen

Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal

2018 Highlights

Dr. Brian Overholser

Calcium/calmodulin-dependent protein kinase II regulation of IKs during sustained β-adrenergic receptor stimulation

Dr. Gregory Hockerman

Molecular Determinants of the Differential Modulation of Ca1.3 by Nifedipine and FPL 64176

Dr. Lynne Taylor 

Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation

Dr. Darci Trader

Development and Application of a Sensitive Peptide Reporter to Discover 20S Proteasome Stimulators

Dr. Michael Murray

Association Between Medication Adherence and Outcomes of Heart Failure

Dr. Elizabeth Topp 

Effects of Drying Process on an IgG1 Monoclonal Antibody Using Solid-State Hydrogen Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS)

Dr. Stephen Byrn

Local Structure of Ion Pair Interaction in Lapatinib Amorphous Dispersions characterized by Synchrotron X-Ray diffraction and Pair Distribution Function Analysis

2017 Highlights

Dr. Andy Tao

Identification of Upstream Kinases by Fluorescence Complementation Mass Spectrometry

Dr. Noll Campbell

Adherence and Tolerability of Alzheimer's Disease Medications: A Pragmatic Randomized Trial

Dr. Danzhou Yang

Insight into the Complexity of the i-Motif and G-Quadruplex DNA Structures Formed in the KRAS Promoter and Subsequent Drug-Induced Gene Repression

Dr. Lynne Taylor 

Insights into Nano- and Micron-Scale Phase Separation in Amorphous Solid Dispersions Using Fluorescence-Based Techniques in Combination with Solid State Nuclear Magnetic Resonance Spectroscopy

Dr. Emily Dykhuizen

Individual Bromodomains of Polybromo-1 Contribute to Chromatin Association and Tumor Suppression in Clear Cell Renal Carcinoma

Dr. Kimberly Plake

The association between family caregivers’ involvement in managing older adults’ medications and caregivers’ information-seeking behavior

Drs. Watts and Lill

Molecular Modeling Evaluation of the Enantiomers of a Novel Adenylyl Cyclase 2 Inhibitor

Dr. Tonglei Li

Impact of surfactant treatment of paclitaxel nanocrystals on biodistribution and tumor accumulation in tumor-bearing mice

2016 Highlights

Dr. Michael Wendt

FGFR signaling maintains a drug persistent cell population following epithelial-mesenchymal transition

Dr. Michael Kays

Population Pharmacokinetics and Pharmacodynamics of Meropenem in Non-Obese, Obese, and Morbidly Obese Patients

Dr. Chang-Deng Hu

Protein arginine methyltransferase 5 functions as an epigenetic activator of the androgen receptor to promote prostate cancer cell growth

Dr. Yoon Yeo

Intraperitoneal chemotherapy of ovarian cancer by hydrogel depot of paclitaxel nanocrystals

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